美国杜克大学2023年招聘研究科学家（对细菌感染先天免疫的分子机制）

杜克大学（Duke University），简称“Duke”或“杜克”，创建于1838年，坐落于美国北卡罗来纳州的达勒姆，是一所私立综合研究型大学。杜克大学为全球大学高研院联盟和美国大学协会成员，官方吉祥物为“蓝魔”（Blue Devil）。

RESEARCH SCIENTIST MIAO LABORATORY AT DUKE UNIVERSITY

Duke University

RESEARCH SCIENTIST MIAO LABORATORY AT DUKE UNIVERSITY

Work Arrangement:

Requisition Number: 230877

Regular or Temporary: Regular

Location:

Durham, NC, US, 27710

Personnel Area: MEDICAL CENTER

Date: Apr 6, 2023

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

The Miao laboratory at Duke University is seeking a highly motivated and well experienced researcher to join our team to investigate the mechanisms of innate immunity and regulated cell death against bacterial infection. The successful candidate will conduct research to investigate the host-pathogen interaction during bacterial infection. The position involves working in BSL-2 conditions for conducting immunology research using molecular biology, bacteriology, and tissue culture. We require a PhD degree with at least 10 years' experience or for this position. Preference will be given to candidates with skills and experience directly relevant to our research, such as mouse models and flow cytometry.

Responsibilities:

Conduct research to investigate the molecular mechanisms of innate immunity against bacterial infections.

Primarily collaborate with a postdoc in the lab to conduct experiments. In addition, assist with the training of graduate students and other researchers in the lab.

Design and execute experiments, analyze data, and interpret results.

Oversee projects and communicate findings to the principal investigator and postdoc.

Prepare manuscripts that describe the experimental findings and conclusions for publication in peer-reviewed journals.

Stay up to date with new developments in the field by reviewing scientific literature, including journals and abstracts. Use this information to help design and develop new procedures and techniques.

Perform other related duties incidental to the work described herein.

Requirements:

Ph.D. in Immunology, Microbiology, Molecular Biology, or a related field.

Strong background with molecular biology techniques, including RNA/DNA isolation, qPCR, Western blotting, and cloning.

Strong background with confocal microscopy.

Strong background with flow cytometry.

Strong background with gene targeting technology, CRISPR knockout and knock- in.

Experience with MALDI-TOF-MS and LC-MS/MS protein analysis.

Experience with in vitro and in vivo models.

Proficiency in data analysis, including GraphPad Prism, Photoshop, Office, Image J, Image Lab, SnapGene, and FlowJo.

Excellent communication and writing skills.

Ability to work independently and as part of a team.

Preferred Qualifications:

Experience with animal models of bacterial infection.

Experience with high-throughput sequencing and analysis of RNA-Seq data.

This is a full-time appointment. The successful candidate will have access to state-of-the-art research facilities and will work closely with a highly collaborative and interdisciplinary research team.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Nearest Major Market: Durham Nearest Secondary Market: Raleigh

RESEARCH SCIENTIST MIAO LABORATORY AT DUKE UNIVERSITY

Work Arrangement:

Requisition Number: 230877

Regular or Temporary: Regular

Location:

Durham, NC, US, 27710

Personnel Area: MEDICAL CENTER

Date: Apr 6, 2023

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