英国利兹大学2023年招聘博士后职位（生物物理学/CryoEM）

利兹大学（University of Leeds），是一所位于英国利兹的公立综合性研究型大学、世界百强名校，英国红砖大学，是罗素大学集团，世界大学联盟、国际大学气候联盟、欧洲大学协会、英联邦大学协会、中英大学工程教育与研究联盟、RENKEI、N8大学联盟、白玫瑰大学联盟成员。利兹大学商学院获AACSB、EQUIS和AMBA三重认证，是全球商学院网络、“一带一路”商学院联盟、中欧商校联盟成员。

Research Fellow in Biophysics/CryoEM

University of Leeds

Job Description

Are you looking to apply your skills in Biophysics and CryoEM/ET to gain a new molecular understanding of the structure of amyloid aggregates and help to develop new routes to combat amyloid diseases?

We are looking for an outstanding postdoctoral research fellow to join our interdisciplinary team that is investigating how proteins aggregate into amyloid fibrils, the link between disease-relevant mutations and post-translational modifications and fibril structure, and how these aggregates perturb cells. This Wellcome-funded role is to use cryoEM/ET, supported with other biophysical and computational analyses, to understand amyloid fibril structure and dynamics. This will help to reveal the mechanisms by which disease-relevant mutations and post-translational modifications effect changes in amyloid aggregate formation and the consequences of aggregation on cellular function.

You will be based in the laboratories of Professors Sheena Radford and Neil Ranson, and work closely with other members of the amyloid team (funded by BBSRC, the Royal Society, MRC and Wellcome). You should have a PhD (or be close to completing one) in Structural Biology, Biochemistry, Biophysics or a related discipline, with extensive experience of using cryoEM backed up with other biophysical and computational methods to elucidate biological mechanisms.

Further information about the project and our recent publications is available in the additional information document.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.

To explore the post further or for any queries you may have, please contact:

Professor Sheena Radford, Astbury Professor of Biophysics

Tel: +44 (0)113 343 3170 | Email: s.e.radford@leeds.ac.uk

Professor Neil A Ranson, Professor of Structural Molecular Biology

Tel: +44 (0)113 343 7065 | Email: n.a.ranson@leeds.ac.uk

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